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02-06-2008, 09:44 PM
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Infiniti514
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Join Date: Jul 2005
Location: Philly
Posts: 48,501
Quote:
Originally Posted by
superdude
okay. Lets talk about t
he
Fischer esterification mechanism in a general form.
First, lets take a generic example of this mecahnism.
Now, the first step involves protonation of the carbonyl oxygen, followed by the nucleophillic attack of the alcohol.
Then a loss and regain of a proton,
followed by loss of water as electrons from the alcohol oxygen kick down to form the double bond. Loss of a proton yields the ester.
So, in review:
man do I ever miss o-chem classes
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