Well your muscles begin to fatigue as you work out so I would imagine it would be better to start with the heavy weights and then step down from there. A good rule of thumb is more weight less reps= more muscle mass while less weight and more reps for toning and more of a streamlined figure.
What types of excersizes are you doing. Compound excersizes such as squats, bench press, etc will be better for bulking up as they work more muscle groups at the same time. Isolated excersizes such as curls, situps, etc are good for toning specific areas as they only work a limited muscle group.
Also, I've heard that you need to change your routine up every 3 to 4 weeks as your muscles develop a learning curve and your results will plateau. Stimulating the same muscle groups in different ways will further develop the entire package.
Oh ya, load on protein within an hour of finishing your workout as your body is like a sponge soaking up nutrients it needs to rebuild cells.
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